The Role of the Spleen in Animals, Disorders and Diseases
In addition to lymph nodes, there are other sites in the body that are dedicated to producing immune cells. The spleen is one of them – a remarkable organ with multiple functions – located in the upper left part of the abdomen, below the rib cage and above the stomach. It is part of the lymphatic system and plays several important roles:
Function of the Spleen | The Spleen in Dogs
- Blood Filtration
One of the primary functions of the spleen is filtering blood. The spleen contains tissue and cells that help remove old, damaged, or abnormal red blood cells from circulation. Macrophages within the spleen engulf and break down these cells, allowing for the removal of cellular debris and maintaining blood quality.
- Storage and Regulation of Blood Flow
- Immune Function
- Iron Metabolism
Diseases | The Spleen in Dogs
Any abnormalities or diseases affecting the spleen can have significant implications for a dog’s health and may require veterinary attention. Common conditions affecting the spleen in dogs include splenomegaly (enlarged spleen), splenic torsion (twisting of the spleen), and splenic tumors.
It is possible to live without a spleen, so in certain pathological conditions and tumors, the spleen is removed and the animal can function normally. That’s why it’s important to preserve the rest of the immune system in the body and take care of overall health.
Learn more about organs that are key to immunity:
Lymph Nodes | Peyer’s Patches



